Role of Botulinum Toxin Type-A (BTX-A)

uqyqfKa /,s jeàu kj;d ,k nela‌àßhd fgdla‌isk

uqyqfKa /<s jeàug" jhia‌.; ùu" m%fõKsl fya;= iy udkisl wd;;sh o mdol fõ' tneúka ueÈ úfha fukau ;reK mqoa.,hka w;r o fï ,la‌IKh oel.; yels h'

uqyqfKa j<j,a iys; ia‌jNdjh fyda l=re,E we;s ùu" fkdfhl=;a wdf,amk .e,aùulska iqj lsÍug fyda ieÛùug fyda yels jqj o"

/,s jeàu kï tf,i ieÛùu wmyiq h' fï i|yd j¾;udkfha § úfYaIfhka p¾u frda. úfYaI{hka úiska uqyqfKa fmaYSkaj,g tkak;a lsÍula‌ isÿ lrkq ,nhs' fuf,i tkak;a lrkafkaBotulinum toxin type A (BTX-A) kï jQ nela‌àßhd fgdla‌iSkhla‌ fõ'

nela‌àßhd fgdla‌iSk fyj;a OQ,l hkq iuyr nela‌àßhd úiska" iෛ, ;=< ksmojd" iෛ,j,ska msg;g ksl=;a lrkq ,nk" Odrlhka f.a ^nela‌àßhd wdidokhg ,la‌ jkakka f.a& idudkH iෛ,Sh l%ShdldÍ;ajhg ndOd muqKqjk ffcj ridhksl úI jk w;r" fïjd kshqfrdfgdla‌iSk" ihsfgdfgdla‌iSk" tkagfrdfgdla‌iSk f,i j¾. l< yels h'
fï m%;sldrfha § Ndú; lrkafka Clostridium botulinum nela‌àßhd u.ska tf,i ksl=;a lrk kshqfrdfgdla‌isk w;ßka A j¾.hhs' fï kshqfrdfgdla‌iSkh ksia‌idrKh lr" msßisÿ lr ydksodhl fkd jk uÜ‌gug ;kql lsÍfuka BTX-A tkak;a o%djKh idod.kq ,nhs' uqyqfKa /,sjeàï we;s jkafka uqyqfKa fmaYs fkdlvjd ixfldapkh ù mej;Sfuks' fuf,i l=uk fmaYshl fyda ixfldapkh ùula‌ isÿ jkqfha" Bg wod< ia‌kdhq wdfõ." fmaYs ;ka;= lrd iïfma%IKh ùfuks' by; kshqfrdfgdaisk fï ia‌kdhq wdfõ. iïfma%IKh wjysr lrhs' uqyqfKa fmaYsj,g fï fgdla‌iskh tkak;a lsÍfuka o tf,i ixfldapkh ùu je<lSfï fya;=fjka uqyqfKa fmaYs o /,ss jeáulg ,la‌ fkd ù bys,a j u mj;S' by; m%;sldrfha moku fuhhs'

k<f,ys" weys neu w;r" weia‌ fomi iy weia‌ jgd" kdifhys kdih iy f;d,a w;r fmfofiys iy f.f,ys we;s jk /,ss i|yd fuf,i m%;sldr lrkq ,nhs' úúO fjf<| kduj,ska tk fï tkak;a o%djKh tkak;a lrk ud;%dj" tkak;a lrkq ,nk ia‌:dkh iy tys ia‌jNdjh iy /,s w;r .eUqr u; r¹ mj;shs' tkak;a lsÍfuka wk;=rej b;d u flá l,lska ^Èk 1)4& m%;sM, oelsh yels uq;a" kj ia‌kdhq ;ka;= we;s ùu;a" ia‌kdhq wdfõ. iïfma%IKh l%ufhka wÆ;ajeähd ùulg ,la‌ ùu;a fya;=fjka udi 3)4lg miqj kej;;a tkak;a lr.ekSug isÿ fõ' uqyqfKa /,s ia‌jNdjhg by; lS ia‌kdhq wdfõ. iïfma%IKh fukau ysre t<shg fnfyúka ksrdjrKh ùu" mßir ¥Il o%jH iy wOYap¾óh ^iug jyd u my< ia‌:rh& iෛ, ñh heu o fya;= jk w;r" tksid we;s jk uqyqfKa /,s jeàu i|yd fï m%;sldrh M, rys; fõ' tneúka m%;sldrhg fmr Bg n,mdk ksYaÑ; fya;=j o oek.ekSu w;HjYH h' ;j o .¾N” iy lsß fok ujqjrekag fukau" ia‌kdhq moaO;sh wdY%s; frda. we;s mqoa.,hkag o fuh tkak;a lrkq fkd ,nhs' tfuka u úgñka E" weia‌m%Ska" ia‌fgfrdhsvuh fkd jk m%;sm%odyl (nonsteroidal antiinflammatory drugs) jeks m%;sleáldrl Tiq iy ðkafika jeks Ydluh ksIamdok Ndú; lrkakkag o" fï m%;sldrhg i;s follg muK fmr isg tu T!IO ;djld,sl j kj;d,Sug ffjoH Wmfoia‌ fokq ,efí' jhia‌.; whg tkak;a lsÍfï§ b;d úfYaI ie,ls,a,la‌ oela‌úh hq;= jk w;r: túg wvq u ud;%dfõ isg m%;sldr lrkq ,efí'

tkak;a lsÍfuka miq wod< ia‌:dkfha isg wfkl=;a ia‌:dk lrd fgdla‌iSk úirKh ùfï fya;=fjka w;=re wdndO f,i ia‌:dk.; r;= ùï" bÈóï" ysi lela‌l=ï" uo fõokd" uqyqfKa fmaYs ÿ¾j, ùu o" WK" wê ixfõol m%;sl%shd (hypersensitivity reactions) .s,Sfï wmyiq;d jeks ;;a;aj o we;s úh yels h' tksid m%;sldrfhka wk;=rej tu ia‌:dk wi, iïndykh fkd lsÍu;a" tfy;a tu tkak;a l< ia‌:dk muKla‌ w;ska ixfldapkh lr fgdla‌iSkh Wrd.ekSu fõ.j;a lsÍu;a u.ska tu ;;a;aj wju lr.; yels h' wefußldkq wdydr yd T!IO md,kdêldrh u.ska j¾I 2004 § wkqu; lr we;s fï tkak; uqyqfKa /,s i|yd isÿ lrk wfkl=;a m%;sldrj,g idfmala‌Ij bla‌uka m%;sM, ,nd §u;a" bla‌ukska iy myiqfjka tkak;a l< yels ùu;a" w;=re m%;sM, wju uÜ‌gfï mej;Su;a jeks jdis i,ik" éqo% Ôj úoHdfõ ;j;a tla‌ úfYaI Ndú;hla‌ fõ'

^wka;¾cd,h weiqfrks&

àkd fmf¾rd

fld<U úYajúoHd,hh

úÿir igyk ) fï ,smsh ffjoH m%;sldr i|yd flfrk ks¾foaYhla‌ fkd jk w;r ifï rEm,djKH lghq;a;l § ieu úg u iqÿiqlï ,;a úfYaI{ ffjoHjrhl= f.ka Wmfoia‌ me;Su iqÿiq h'  

 (vidusara.com)

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